Cannabidiol may indirectly help with weight loss through several mechanisms. First of all, it interacts with the endocannabinoid system (ECS), a cell-signaling network that influences appetite, sleep, muscle growth, metabolism, digestion, and other processes in the human body, explains Healthline. Moreover, it blocks the cannabinoid receptor type 1 (CB1), which in turn may help prevent obesity, according to 2020 research published in the journal Frontiers in Endocrinology. The same source reports that CBD regulates energy metabolism and may increase lipolysis, or fat breakdown.
In clinical studies, CBD has been found to boost energy expenditure and improve the body’s ability to use glucose for fuel, according to the above review. Plus, it seems to decrease insulin and blood sugar levels, which may benefit people with diabetes, obesity, or other metabolic disorders. At the same time, it raises your body’s core temperature, leading to more calories burned. Scientists also believe that CBD facilitates weight loss by bringing down inflammation, a risk factor for obesity and chronic disease.
Another theory states that cannabinoids, including CBD, increase brown fat in the body, according to a 2018 review featured in the International Journal of Molecular Sciences. Brown adipose tissue requires more energy to sustain itself compared to “white” fat and hence can stimulate thermogenesis, or heat production, resulting in weight loss. This type of body fat may protect against diabetes and other metabolic disorders, notes the University of Michigan.